Wednesday, February 21, 2018

UA Researchers: Liquid Brain is Toxic

Posted By on Wed, Feb 21, 2018 at 1:07 PM

When someone suffers a stroke, there is poor blood flow to the brain, and this results in the death of brain cells. Dead fragments of the brain don’t heal like normal muscle or body tissue — they liquify, and this liquid brain stays in the skull, right next to the healthy brain, for a long time.


click to enlarge screen_shot_2018-02-21_at_12.56.20_pm.png

Scientists at the UA’s College of Medicine found this liquefied brain tissue is toxic and can leak into the remaining healthy portion of the brain over time, potentially causing harm.


“Most people probably assume that the brain heals in the same way as other tissues,” said Kristian Doyle, PhD, assistant professor of Immunobiology at UA. “But it doesn’t; dead brain tissue doesn’t just heal and go away like other bodily injuries. Instead it liquefies and remains in this liquefactive state for a long time.”

These new findings may open the door for developing new treatments to fight dementia after a stroke. Roughly 10 million people survive a stroke annually. About one-third of which will develop dementia for unclear reasons. It is hypothesized that if the brain is injured near the hippocampus (the portion of the brain responsible for memory) this slow leak of toxic fluid can cause neuron loss in the brain and lead to memory problems.


“This work really challenges the old paradigms and breaks new ground critical for our understanding of stroke and its consequences,” said doctor Janko Nikolich-Zugich, chair of the UA Department of Immunobiology. “Thanks to this research, we now will be able to consider new and different stroke therapies.”



Tags: , , ,

Comments

Subscribe to this thread:

Add a comment

More by Jeff Gardner

  • Quick Bites

    The best in culinary experiences this week.
    • Nov 14, 2019
  • Reel Indie

    Movies in your local indie theaters.
    • Nov 14, 2019
  • Know Your Product

    Stars Pick Their Top 5! This Week: Black Belt Eagle Scout
    • Nov 14, 2019
  • More »
Today | Thu | Fri | Sat | Sun | Mon | Tue
Beginning Contortion

Beginning Contortion @ Circus Sanctuary

Mondays, 6:45-8 p.m. Continues through Dec. 21

All of today's events | Staff Picks

Staff Pick

TMA Holiday Art Market

The Holiday Art Market brings together more than 100 artisans selling handmade and one-of-a-kind items. Browse original… More

@ Tucson Museum of Art Fri., Nov. 22, 10 a.m.-5 p.m., Sat., Nov. 23, 10 a.m.-5 p.m. and Sun., Nov. 24, 10 a.m.-5 p.m. 140 N. Main Ave.

» More Picks

Submit an Event Listing

Popular Content

  1. Claytoon of the Day: Zelensky Loves It (The Range: The Tucson Weekly's Daily Dispatch)
  2. Things to Do, Nov. 20 (The Range: The Tucson Weekly's Daily Dispatch)
  3. Claytoon of the Day: Hater Chicken Concedes (The Range: The Tucson Weekly's Daily Dispatch)
  4. XOXO: Where to Rock, Wednesday, Nov. 20 (The Range: The Tucson Weekly's Daily Dispatch)
  5. Man Sentenced for 2016 Death of Ann Day (The Range: The Tucson Weekly's Daily Dispatch)

© 2019 Tucson Weekly | 7225 Mona Lisa Rd. Ste. 125, Tucson AZ 85741 | (520) 797-4384 | Powered by Foundation